Ozempic is a gene manipulator; it alters the personality of its users.

Medications that alter gene expression, such as ozempic and GLP-1 drugs, can have serious side effects due to their impact on consciousness, including personality changes, emotional flattening, and loss of enjoyment of life. This effect has led to the term "ozempic personality."

GLP-1 drugs are part of extensive research in the field of genetic medicine, the results of which include the deterioration of the genetic basis of a healthy mind and body, explains Dr. Guy Hatchard. The development and prescription of gene-editing drugs, including mRNA COVID vaccines, is a key component of this development.

The Downfall of the House of Biotechnology

By Dr. Guy Hatchard , April 25, 2026

This is one of the most important articles we have published, not only because it challenges the current tide of polypharmacy being forced upon us, but also because it cites research that reveals the limitations of current interpretations of gene function. DNA has thus far been considered the sole source of life.

Genetic theories construct a computer-like model of life in which our DNA is a self-contained repository of complex, coded information. This model omits the executive role of consciousness, which is obvious to everyone from everyday experience—our choices influence the outcomes. How this occurs is a question that biotechnology has largely neglected, leading to an incomplete understanding of the role of genes and their relationship to our self-understanding. This article explores models that incorporate consciousness into life.

We possess approximately 25.000 genes that perform millions of specific tasks. To enable this multitasking, the genes work together. Imagine a keyboard with 88 keys. When playing, the keys can be struck in combinations, sequences, speeds, and with varying pressure, creating an infinite variety of music. Some of these combinations and sequences are recorded in sheet music and scores, which are essentially blueprints for compositions. But these are far from all the possible works; new pieces are created daily, utilizing the same 88 keys. In fact, musical pieces are not created by pianos, but by human consciousness, which operates throughout the entire body.

How genes function cooperatively is still largely unexplored. This article should be read in conjunction with our Substack article “ The Sacred Cell and Conscious Genes ,” which explains the underlying quantum structure of cells on finer time and space scales and ultimately reveals the existence of consciousness itself. Cells are awake. The conscious heart of cells coordinates life, just as the pianist’s consciousness creates the infinite variety and joy of music.

Drugs that alter gene expression
Ozempic and other GLP-1 inhibitors are currently among the best-selling and most profitable medications. They have rapidly dominated the entire weight-loss market. An estimated 12% of adults in the US (40 million) have already tried various GLP-1 inhibitors for weight loss. Global distribution is projected to exceed 150 million units by the 2030s, representing a revenue of $150 billion.

It was recently discovered that GLP-1 drugs affect appetite by directly altering gene expression . Gene expression is the process by which information stored in DNA is translated into functional products, primarily proteins or RNA. It is well known that every person has a unique genetic signature. Therefore, any drug that affects gene expression will have different effects on groups of people with specific genetic traits. GLP-1 drugs affect gene expression in the liver and pancreas. In most people, these changes slow digestion, but in some with a particular genetic profile, they can lead to food intolerances. For example, some people with certain gene sequences develop an intolerance to alcohol. A woman from Suffolk, writing under a pseudonym, told the Mail on Sunday :

Even a few glasses of white wine can now unexpectedly leave her feeling down and emotionally unstable, triggering reactions she hardly recognizes. And, to her shame, these reactions now lead to the most unexpected and intense arguments with her husband, with whom she used to have a very happy relationship.

Consider the effects on their personality and consciousness. The Washington Post headlines: " What is an 'ocemic personality' and why does it make life feel so lifeless? " and reports: "Doctors and patients are reporting on social media a kind of emotional numbing while taking GLP-1 medications." This includes a loss of enjoyment in life, not just in eating, but in other things like reading, listening to music, dancing, gardening—or even sex. A kind of paralyzing apathy spreads through their lives.

The cause of these distressing psychological effects of GLP-1 medications is not yet fully understood. It lies in the way these medications alter gene expression, which is closely linked to our mental state. A study published in Nature, titled " Genetic predictors of weight loss and side effects of GLP-1 receptor agonists ," found that people with certain genetic profiles may experience specific side effects and/or no weight loss from the medication.

In fact, GLP-1 inhibitors are just one of many types of gene-modifying drugs developed this century. Altering gene expression is associated with a wide range of side effects, which can become very serious immediately or over time. For example, in 2023, a new class of drugs to reduce amyloid plaques was introduced and prescribed to dementia patients, including the active ingredients lecanemab (Leqembi), donanemab (Kisunla), and aducanumab (Aduhelm). These drugs alter gene expression by triggering a "transcription program" in the brain's microglia immune cells. Studies have now shown that 20% of patients experience life-threatening brain swelling and bleeding. Although the drugs reduce the concentration of amyloid plaques, they often exacerbate symptoms of confusion. The reactions are so extreme that authorities in the UK and the US are considering withdrawing their marketing authorization. Whether these effects are reversible is not yet known.

However, this is known in the case of the osteoporosis drug Prolia (also known as denosumab), which is prescribed to postmenopausal women with osteoporosis and a high risk of fracture. Denosumab works by altering the expression of genes responsible for bone metabolism. The drug was introduced in 2010. As early as 2011, New Zealand health journalist Gillian Sanson warned that the drug was likely to cause unhealthy changes in bone structure and increase the risk of cancer. A study published in 2024, titled " Analysis of the adverse effects of denosumab (Prolia) in osteoporosis based on the FDA Adverse Event Reporting System (FAERS), " found a very high rate of adverse effects from the drug in a staggering 27 organ systems. These side effects include, among others, abnormally low blood calcium levels, abnormal bone density, connective tissue weakness, eczema, nervous system disorders, psychiatric illnesses, spinal deformities, immobility, menopausal symptoms, an increased risk of infection, heart disease, and metabolic disorders. The wide range of serious, systemic side effects is characteristic of drugs that alter gene expression. In other words, the fundamental coordination and effectiveness of gene expression can be impaired. In fact, we now know that discontinuing denosumab once it has been started is not straightforward or safe, as it causes irreversible changes in gene expression that impair the body's ability to heal bone fractures—the exact opposite of the drug's intended effect.

mRNA injections are part of the trend
In summary, new classes of drugs that alter gene expression are being developed and widely prescribed. These drugs exhibit very high rates of short- and long-term physiological side effects, often accompanied by serious psychological changes. This is not merely a worrying development, but a trend in medicine where drugs of uncertain efficacy are "tested" on the public without informing patients about the significant health risks. The drugs mentioned above are not isolated cases; they are part of a broader field of research driving genetic medicine, the consequences of which, we should be aware, include a deterioration of the genetic foundations of health and life as a whole.

mRNA-based COVID vaccines play a significant role in this trend. Public skepticism towards mRNA vaccines stems from personal experiences and research findings that suggest a lack of efficacy and safety for these so-called "vaccines." A growing number of studies are published weekly that challenge the claims made regarding their safety and efficacy. Examples include the study " A Reanalysis of the FDA's Benefit–Risk Assessment of Moderna's mRNA-1273 COVID Vaccine Based on a Model Incorporating Benefits Derived from Prior COVID Infection " and the study " Temporal patterns of all-cause mortality among US nursing home residents across COVID-19 vaccination strata, May 2022–June 2023. " Both studies demonstrate that the initial assumptions about safety and the analytical methods used to assess them were structurally inadequate for analyzing the available datasets and drawing sound conclusions.

I cannot overstate the importance of revising our paradigm of gene function. The idea that DNA completely encodes the secret of life is so deeply ingrained in the collective consciousness that any deviation from this paradigm has become almost unthinkable. Articles in major media outlets regularly report that cures for nearly all genetically based diseases are imminent. This is unrealistic thinking that ignores not only the reality of rigorous scientific findings but also our own everyday experience that consciousness or perception defines life. How DNA enables the expression of consciousness remains a mystery, making biotechnological experiments the greatest risk humanity has ever faced. In classical depictions of life, the human body is described as a chariot drawn by five horses, symbolizing our five senses. The mind is the charioteer. Altering gene expression in this analogy is like a highwayman hijacking the horses and steering the body in a completely unpredictable direction that does not serve the purposes of the human mind. Think about it: Our mind is the most valuable thing we possess. Nobody wants to lose their mind.

There is an urgent need to question the fundamental assumptions of the genetic paradigm. As the poet and Nobel laureate Rabindranath Tagore warned in his moving allegory "Arrival" (excerpt follows):

One of us said: "The King of the Night is coming."

We just laughed and said, "No one will come again until tomorrow morning."

And while the night was still dark, a loud, nearby drumming arose.

Someone shouted to everyone: "Wake up, wake up, don't waste any more time!"

We have reached a point where many highly qualified scientists have begun to collect data, ask questions, and voice their opinions. Now it is time to wake up, listen, and, as Tagore ends his poem, “no longer hesitate.”

Guy Hatchard, PhD, is a New Zealander who was formerly a senior manager at Genetic ID, a global food testing and safety company (now known as FoodChain ID).

(via Exposing The Darkness)