The article "Inability to work after COVID-19 vaccination» which was published in the journal Public Health (paid, but here as Preprint available from November last year) and in which data from the “CoVacSer” cohort study is analyzed, which was carried out from Würzburg to observe the effects of Covid infection and vaccination on healthcare workers. Of 1831 CoVacSer participants surveyed about their experiences with vaccination between September 29, 2021 and March 27, 2022, 1704 met the criteria for inclusion in the present study. So we're looking at the effects of the first, second and third doses.
COVID-19 vaccination has emerged as a key strategy for containing the spread and severity of SARS-CoV-2 infections, particularly among [health care workers]. However, vaccine-related incapacity could overwhelm the public health system and must be taken into account as part of this important prevention strategy. Vaccine-related staff absences need to be taken into account in light of future COVID-19 booster vaccination campaigns and the challenges posed by the ongoing COVID-19 pandemic.
The CoVacSer sample is predominantly female (87%); only a minority (18,6%) were physicians. With an average age of 39, she is also relatively young and healthy.
The vast majority of all participants in the cohort received BioNTech/Pfizer for each of the three doses. Across all three doses and all 1704 participants, the vaccinations resulted in a total of 1550 days of illness. Here is the table of average sick days for each dose:
And here is the percentage of healthcare workers who claim some amount of sick leave for each dose:
Overall, the booster vaccinations resulted in 27,9% of the entire sample taking at least one day off work. Of the 21 participants who received the first dose of AstraZeneca, as many as 11, or 52%, took sick leave. Moderna also did significantly worse than the BioNTech average: 106 of 255 participants who received it as a third dose, or 46%, were sent home to recover.
The broader subset of healthcare workers who took medication to relieve symptoms after vaccination shows the same picture. After the third dose, the vast majority of all participants (86%) took medication to relieve the acute symptoms of vaccination:
The breakdown by gender is interesting: men were less likely to take medication after the first and second doses (16,6% vs. 24% and 31,5% vs. 49,6%, respectively), but after the third dose this gender difference disappeared. However, men were consistently less likely to take sick leave after each dose.
The authors conclude that “COVID-19 vaccination has a non-negligible impact on the availability of healthcare workers” and that the increased immune response to each further vaccination is likely responsible for the escalating symptoms. This is only about acute, immediate reactions to the vaccination - not longer-term side effects or other more serious adverse events. The results of the study are clearly confirmed by the general public's overwhelming reluctance to receive further vaccinations after the booster vaccination. Even if everything goes well, the vaccines make many people feel sick and the effect becomes stronger and stronger with each subsequent vaccination.
(via eugyppius: a plague chronicle)